Our postdoctoral work by Dr. Yin has proved her hypothesis and elegant art of nanotechnology to perform SERS+PTT+Chemotherapy for cancer! A multilayered mesoporous gold/SiO2-based nanostructure is presented to possess ultrasensitive SERS detection performance with large capacity to encapsulate doxorubicin (loading efficiency = 34.1%) and high photothermal conversion efficiency (85.5%). Together with tumor-targeting moiety, this nanoplatforms enables on-site detection of tumors and single-beam NIR excitation to irradicate tumor cells without recurrence one-month after the treatment.
This excellent work has been published in Small. More details can be found on https://onlinelibrary.wiley.com/doi/full/10.1002/smll.202206762